### Changeux, Jean-Pierre
| Name | Jean-Pierre Changeux |
| --------- | --------- |
| Birth Date | 06 April 1936 |
| Birth Place | Domont, France |
| Known for | Biology |
| Field | Neurobiology, Molecular Biology, Neuroscience |
| Institutions | Collège de France, Pasteur Institute, Columbia University
| Twitter | - |
| LinkedIn | - |
| Awards | Balzan Prize, Lasker Award, Grand Prix scientifique de la Fondation NRJ |
| Recent Projects | Developing new therapies for neurological disorders, studying the role of nicotine in the brain |
#### Biography:
Jean-Pierre Changeux is a French neurobiologist, molecular biologist, and neuroscientist. He is best known for his work on the molecular structure of the nicotinic acetylcholine receptor and the role of neuronal networks in learning and memory. He is a professor at the Collège de France, director of the Neuroscience Center at the Pasteur Institute, and an adjunct professor at Columbia University.
Changeux was born on 6 April 1936 in Domont, France. He studied medicine at the University of Paris and received his M.D. degree in 1960. In 1964 he received a D.Sc. degree in neurophysiology from the University of Paris. After completing his postdoctoral training at the National Institutes of Health in Bethesda, Maryland, he returned to France in 1967 and became a professor at the Collège de France.
Changeux's research has focused on the molecular structure of the nicotinic acetylcholine receptor. This receptor is a protein that is located on the surface of nerve cells and is responsible for transmitting signals from one nerve cell to another. Changeux and his colleagues have used X-ray crystallography to determine the three-dimensional structure of the receptor, and they have also identified the amino acid residues that are responsible for binding to nicotine. This work has provided important insights into the molecular basis of synaptic transmission and the development of new therapies for neurological disorders.
In addition to his work on the nicotinic acetylcholine receptor, Changeux has also studied the role of neuronal networks in learning and memory. He has shown that the formation of new memories is associated with changes in the structure and function of neuronal networks. This work has led to a new understanding of the neural basis of learning and memory, and it has also provided new insights into the development of therapies for neurodegenerative disorders.
Changeux is a member of the French Academy of Sciences, the U.S. National Academy of Sciences, and the Royal Society of London. He has received numerous awards for his research, including the Balzan Prize, the Lasker Award, and the Grand Prix scientifique de la Fondation NRJ.